Akademik Veri Yönetim Sistemi
Asian Journal of Surgery, cilt.24, sa.2, ss.193-196, 2001 (Scopus)
Schwannomas are neurogenic tumors that can arise from different organs and tissues. They are rarely seen within the gastrointestinal tract, but when they do occur, the most common site is stomach. Two cases encountered in a 4.5 year period are presented here. These tumors are usually asymptomatic at the beginning, but may rarely cause hemorrhage due to ulceration of the overlying mucosa. They sometimes present as mass lesions. When hemorrhage is the first symptom, upper endoscopy is important in the initial evaluation. But when it is asymptomatic, barium meal or computerized tomography can be useful. Histopathologic diagnosis is based on features of palisading nuclei with spindle-cell morphology and hyalinized vessels. Immunohistochemical stains, especially for S-100 protein, CD34, desmin and actin must be done for the differentiation from the other stromal tumors of the stomach such as leiomyomas. Although the recurrence rate is too small, complete excision of the tumor with free margins including local resection or enucleation is necessary for the adequate treatment. Prognosis after treatment is good.