Synthesis of ferrocenyl pyrazoles by the reaction of 3-ferrocenylpropynal with hydrazinium salts

ZORA M., Pinar A. N., Odabaşoǧlu M., Büyükgüngör O., Turgut G.

Journal of Organometallic Chemistry, vol.693, no.1, pp.145-154, 2008 (SCI-Expanded, Scopus) identifier

  • Publication Type: Article / Article
  • Volume: 693 Issue: 1
  • Publication Date: 2008
  • Doi Number: 10.1016/j.jorganchem.2007.10.035
  • Journal Name: Journal of Organometallic Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.145-154
  • Keywords: Condensation, Cyclization, Ferrocene, Hydrazine, Propynal, Pyrazole
  • Manisa Celal Bayar University Affiliated: No

Abstract

Synthesis of ferrocenyl-substituted pyrazoles via the reaction between 3-ferrocenylpropynal and hydrazinium salts is described. Depending upon the substitution pattern of hydrazine derivative, the reaction affords 1-alkyl/aryl-5-ferrocenylpyrazoles and/or 1-alkyl/aryl-3-ferrocenylpyrazoles. Structures of 5-ferrocenyl-1-phenyl-1H-pyrazole, 1-benzyl-5-ferrocenyl-1H-pyrazole and 2-(3-ferrocenylpyrazol-1-yl)ethanol were identified by X-ray crystallography. © 2007 Elsevier B.V. All rights reserved.