Scaling-up of Haematococcus pluvialis production in stirred tank photobioreactor

DENİZ CAN İ.

Bioresource Technology, vol.310, 2020 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 310
  • Publication Date: 2020
  • Doi Number: 10.1016/j.biortech.2020.123434
  • Journal Name: Bioresource Technology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, PASCAL, Aqualine, Aquatic Science & Fisheries Abstracts (ASFA), BIOSIS, Biotechnology Research Abstracts, CAB Abstracts, Chemical Abstracts Core, Compendex, EMBASE, Environment Index, Food Science & Technology Abstracts, Geobase, INSPEC, MEDLINE, Pollution Abstracts, Veterinary Science Database, Civil Engineering Abstracts
  • Keywords: Antioxidant activity, Haematococcus pluvialis, Scale-up, Stirred tank photobioreactors
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

The objective of this study was to evaluate three most common scale-up criteria for Haematococcus pluvialis production from cultivation bottles to 2 and 10 L of stirred tank PBRs. Constant volumetric power input (P/V) was found to be the most suitable criterion for H. pluvialis production. Total carotenoid amount per biomass concentration in 2 L and 10 L stirred tank PBRs were determined to be 4.57 mg/g and 4.77 mg/g, respectively. Antioxidant activity of total carotenoids extracted from H. pluvialis was also higher at constant P/V criterion where 46.91% inhibition rate with a total phenolic content of 11.76 mg gallic acid/L was achieved. Obtained results could be used to expand the bioproduction of H. pluvialis and its extracts in commercial scale.