Unexpected Metastatic Localizations of Prostate Cancer Determined by68Ga PSMA PET/CT: Series of Four Cases 68 Ga PSMA PET/BT’de Saptanan Prostat Kanserinin Nadir Metastaz Lokalizasyonları: Dört Olgu

MÜTEVELİZADE G., Sezgin C., Gümüşer G., Sayit E.

Molecular Imaging and Radionuclide Therapy, cilt.31, sa.3, ss.223-226, 2022 (Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 31 Sayı: 3
  • Basım Tarihi: 2022
  • Doi Numarası: 10.4274/mirt.galenos.2021.41033
  • Dergi Adı: Molecular Imaging and Radionuclide Therapy
  • Derginin Tarandığı İndeksler: Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.223-226
  • Anahtar Kelimeler: Prostate cancer, unexpected, metastases, Ga-68 PSMA PET/CT
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Prostate-specific membrane antigen (PSMA) is a transmembrane protein with overexpression in most prostate cancer cells. Gallium-68-(68Ga) PSMA positron emission tomography/computed tomography (PET/CT) imaging is a game-changer in the management of prostate cancer.68Ga PSMA PET/CT scan is advanced and a promising radioligand has high sensitivity in determining lesions of prostate cancer with a high tumor to background ratio. The most common areas of metastasis are the bone and pelvic lymph nodes. The prognosis of prostate cancer is mainly determined by the status of metastases. The presence and the localization of metastases affects treatment planning. In our cases, we presented some examples of uncommon sites of metastases such as the brain, adrenal glands, penis and orbit. Improvements in imaging techniques, such as68Ga PSMA PET/CT have led to the possibility to make more determination of rare metastase sites in prostate cancer patients.