Klinik Psikofarmakoloji Bulteni, cilt.11, sa.2, ss.111-115, 2001 (Scopus)
Quetiapine is an atypical antipsychotic which has been recently submitted for clinical use in Turkey. Studies revealed that quetiapine is effective on the positive and negative symptoms of schizophrenia and has less side effects compared to conventional antipsychotics. In this article 5 cases, who had been followed with diagnosis of schizophrenia for a long time and had acute exacerbation in positive symptoms during quetiapine treatment, are presented. In literature no articles about side effects of quetiapine were found. The possible reasons of this condition occurring in Turkey was discussed and a study on the pharmacokinetic properties of quetiapine based on this report is proposed.