Radical radiotherapy in advanced stage non-small cell lung cancer:: evaluation of 332 cases


YALMAN D., Arican A., Karakoyun Ö., Karadogan I., Denizli V., Haydaroglu A.

2nd Congress of the Balkan-Union-of-Oncology, İzmir, Türkiye, 10 - 14 Eylül 1998, ss.291-296, (Tam Metin Bildiri) identifier

  • Yayın Türü: Bildiri / Tam Metin Bildiri
  • Basıldığı Şehir: İzmir
  • Basıldığı Ülke: Türkiye
  • Sayfa Sayıları: ss.291-296
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Between January 1990 and December 1996, 332 cases of advanced stage NSCLC who referred to our department for radical RT were assessed retrospectively. Median age was 59 (range: 31-85); 26.5% were stage IIIa and 73.5% were stage IIIB. Complete response rate, response rate higher than 50% and lower than 50% after radiotherapy were 14.1%, 33.4% and 39.5% respectively. Median follow-up duration was 21 months (12-71 months). Median overall and disease-free survival durations were 13 and 8 months; 2 and 5 year overall and disease-free survival rates were 19.5%, 7.2% and 12.0%, 6.5% respectively. In univariate analysis prognostic factors affecting overall survival were complete response to radiotherapy (p<0.0001); tumor localisation in superior lobes (p=0. 05); age younger than 65 years (p<0.0001) and chemotherapy administration after radiotherapy whereas in multivariate analysis response to radiotherapy (p=0.0008); tumor localisation (p=0.049) and age (p=0.015) were the prognostic factors affecting overall survival.