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2nd Congress of the Balkan-Union-of-Oncology, İzmir, Turkey, 10 - 14 September 1998, pp.291-296, (Full Text)
Between January 1990 and December 1996, 332 cases of advanced stage NSCLC who referred to our department for radical RT were assessed retrospectively. Median age was 59 (range: 31-85); 26.5% were stage IIIa and 73.5% were stage IIIB. Complete response rate, response rate higher than 50% and lower than 50% after radiotherapy were 14.1%, 33.4% and 39.5% respectively. Median follow-up duration was 21 months (12-71 months). Median overall and disease-free survival durations were 13 and 8 months; 2 and 5 year overall and disease-free survival rates were 19.5%, 7.2% and 12.0%, 6.5% respectively. In univariate analysis prognostic factors affecting overall survival were complete response to radiotherapy (p<0.0001); tumor localisation in superior lobes (p=0. 05); age younger than 65 years (p<0.0001) and chemotherapy administration after radiotherapy whereas in multivariate analysis response to radiotherapy (p=0.0008); tumor localisation (p=0.049) and age (p=0.015) were the prognostic factors affecting overall survival.