2nd Congress of the Balkan-Union-of-Oncology, İzmir, Türkiye, 10 - 14 Eylül 1998, ss.291-296, (Tam Metin Bildiri)
Between January 1990 and December 1996, 332 cases of advanced stage NSCLC who referred to our department for radical RT were assessed retrospectively. Median age was 59 (range: 31-85); 26.5% were stage IIIa and 73.5% were stage IIIB. Complete response rate, response rate higher than 50% and lower than 50% after radiotherapy were 14.1%, 33.4% and 39.5% respectively. Median follow-up duration was 21 months (12-71 months). Median overall and disease-free survival durations were 13 and 8 months; 2 and 5 year overall and disease-free survival rates were 19.5%, 7.2% and 12.0%, 6.5% respectively. In univariate analysis prognostic factors affecting overall survival were complete response to radiotherapy (p<0.0001); tumor localisation in superior lobes (p=0. 05); age younger than 65 years (p<0.0001) and chemotherapy administration after radiotherapy whereas in multivariate analysis response to radiotherapy (p=0.0008); tumor localisation (p=0.049) and age (p=0.015) were the prognostic factors affecting overall survival.