The relationship of muscle İnjury frequency with the myosin light chain Kinase (MLCK) gene and sports İnjury anxiety association of MLCK polymorphisms with sports İnjury anxiety

ÖZGÜNEŞ Ş., ZEKİOĞLU A., ÇAM F. S., Gökmen M. H.

Research in Sports Medicine, 2025 (SCI-Expanded, Scopus) identifier identifier identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2025
  • Doi Number: 10.1080/15438627.2025.2559324
  • Journal Name: Research in Sports Medicine
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, IBZ Online, CAB Abstracts, CINAHL, MEDLINE, SportDiscus
  • Keywords: anxiety, MLCK Gene, muscle injury, polymorphism
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

The purpose of the current study is to determine the relationship between the Myosin Light Chain Kinase (MLCK) gene and muscle injuries and to reveal athletes’ injury status both molecularly and psychologically using the Sports Injury Anxiety Scale. The participants of the study are 23 female and 39 male athletes who have been previously engaged in sports or are currently active in sports. The participants are aged 18–65 and participated in the study on a volunteer basis. In the current study, when the relationship between injury anxiety, genetics and injury frequency in athletes was examined, a significant correlation was found between the MLCK C49T gene region and anxiety of causing disappointment (D total) as follows: the C/C genotype 12.4 ± 2.69 C/C genotype: 4.17 ± 2.04 = 0.032(m) (p < 0.05). These results suggest that there may be a relationship between injury and some psychological and environmental factors.