Effects of cilazapril on endothelial function and pulmonary hypertension in patients with congestive heart failure.

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Tavli T., Gocer H.

Japanese heart journal, cilt.43, sa.6, ss.667-674, 2002 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 43 Sayı: 6
  • Basım Tarihi: 2002
  • Doi Numarası: 10.1536/jhj.43.667
  • Dergi Adı: Japanese heart journal
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.667-674
  • Anahtar Kelimeler: endothelial function, cilazapril, pulmonary hypertension, congestive heart failure
  • Açık Arşiv Koleksiyonu: AVESİS Açık Erişim Koleksiyonu
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Flow-mediated vasodilation (FMV), brachial artery flow (BAF), and brachial artery diameter were evaluated in 30 patients with congestive heart failure before and after cilazapril treatment. While mean pulmonary artery pressure and pulmonary capillary wedge pressure decreased significantly, flow-mediated vasodilation and left ventricular ejection fraction increased significantly following cilazapril administration (P < 0.001). Brachial artery diameter and brachial artery flow did not change following the treatment period (P > 0.05). In conclusion, short-term cilazapril administration improved endothelial function and pulmonary pressure in patients with congestive heart failure.