Diffuse idiopathic skeletal hyperostosis in patients with prediabetes Hiperostosis esquelética idiopática difusa en pacientes con prediabetes

Altıntas A., Acar E. A., USLU S., ÖRGÜÇ İ. Ş., HEKİMSOY Z., PIRILDAR T.

Reumatologia Clinica, 2025 (ESCI, Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Basım Tarihi: 2025
  • Doi Numarası: 10.1016/j.reuma.2025.502017
  • Dergi Adı: Reumatologia Clinica
  • Derginin Tarandığı İndeksler: Emerging Sources Citation Index (ESCI), Scopus, EMBASE, MEDLINE, DIALNET
  • Anahtar Kelimeler: Diffuse idiopathic skeletal hyperostosis (DISH), Prediabetes, Radiograph
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Objective: To investigate the frequency of diffuse idiopathic skeletal hyperostosis (DISH) in patients with prediabetes. Material and methods: A total of 166 prediabetic patients were prospectively evaluated, of whom 67 with symptoms suggestive of DISH underwent thoracic and lumbar radiography. DISH was diagnosed according to Resnick and Niwayama criteria. Demographic, clinical and laboratory data were analyzed. Results: DISH was diagnosed in 9 patients (13.4% of symptomatic; 5.4% overall). Patients with DISH were older and more frequently hypertensive compared to those without DISH (p = 0.004 and p = 0.047, respectively). Other parameters such as body mass index, fasting glucose, and smoking showed higher trends in the DISH group but did not reach statistical significance. Conclusion: This is the first study to examine DISH in a prediabetic population. Our findings suggest a possible association between DISH and prediabetic status, although further studies are needed to confirm this relationship.