Therapeutic Hotline: Treatment of prurigo nodularis and lichen simplex chronicus with gabapentin

Gencoglan G., İNANIR I., GÜNDÜZ K.

Dermatologic Therapy, cilt.23, sa.2, ss.194-198, 2010 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 23 Sayı: 2
  • Basım Tarihi: 2010
  • Doi Numarası: 10.1111/j.1529-8019.2010.01314.x
  • Dergi Adı: Dermatologic Therapy
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.194-198
  • Anahtar Kelimeler: gabapentin, lichen simplex chronicus, prurigo nodularis, pruritus, therapy
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Psychocutaneous conditions are frequently encountered in dermatology practice. Prurigo nodularis and lichen simplex chronicus are two frustrating conditions that are classified in this category. They are often refractory to classical treatment with topical corticosteroids and antihistamines. Severe, generalized exacerbations require systemic therapy. Phototherapy, erythromycine, retinoids, cyclosporine, azathiopurine, naltrexone, and psychopharmacologic agents (pimozide, selective serotonin reuptake inhibitor antidepressants) were tried with some success. Here five cases with lichen simplex chronicus and four cases with prurigo nodularis, who responded well to gabapentin, are presented. © 2010 Wiley Periodicals, Inc.