Incontinentia pigmenti Stage 1 is not simply vesiculo-bullous but vesiculo-pustular

ÇETİNARSLAN T., Fölster-Holst R., Van Gysel D., Buchner M., Happle R.

Pediatric Dermatology, vol.41, no.1, pp.182-183, 2024 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 41 Issue: 1
  • Publication Date: 2024
  • Doi Number: 10.1111/pde.15465
  • Journal Name: Pediatric Dermatology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts
  • Page Numbers: pp.182-183
  • Keywords: incontinentia pigmenti, inflammatory, newborn, pustule, Stage 1, vesiculopustular
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

Incontinentia pigmenti (IP) is a rare X-linked dominant, male-lethal disorder characterized by pathognomic skin lesions. As described in the literature the typical cutaneous changes follow the pattern of Blaschko's lines and develop in four stages that usually start at birth. Stage 1 is called vesicular, bullous or inflammatory. The vesicles are rapidly filled with eosinophils and thus turn into pustules. Thus, the term “pustular” is relevant to the first phase of IP, and the stage can be considered as “vesiculopustular/inflammatory” to be more precise than “vesicular” or “bullous.”.