Maternal carriage and antimicrobial resistance profile of group B Streptococcus

Arisoy A., Altinişik B., Tünger Ö., KURUTEPE S., Ispahi Ç.

Infection, vol.31, no.4, pp.244-246, 2003 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 31 Issue: 4
  • Publication Date: 2003
  • Doi Number: 10.1007/s15010-003-3182-6
  • Journal Name: Infection
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.244-246
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

Background: The aim of this study was to determine the prevalence of group B Streptococcus (GBS) colonization and to evaluate the antimicrobial resistance profile in women in the third trimester of pregnancy. Materials and Methods: A total of 310 pregnant women, referred in weeks 35 to 37 of gestation, were screened for GBS colonization during a 10-month period. Samples were collected from the vagina and the rectum. Results: The colonization rate was 10.6% and 22 women (66.7%) had both positive vaginal and rectal cultures. Rates of GBS colonization were significantly Lower in patients aged 24 years or older and in those with a third or later pregnancy. None of the isolates were resistant to penicillin and ampicillin, whereas 21.2% and 9.1% showed resistance to erythromycin and clindamycin, respectively. Conclusion: Screening and antimicrobial susceptibility testing of GBS during pregnancy are important to guide appropiate therapy.