Do walking programs affect C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand?


Esen H., Büyükyazi G., ULMAN C., TANELİ F., Ari Z., Gözlükaya F., ...Daha Fazla

Turkish Journal of Biochemistry, cilt.34, sa.3, ss.178-186, 2009 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 34 Sayı: 3
  • Basım Tarihi: 2009
  • Dergi Adı: Turkish Journal of Biochemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, TR DİZİN (ULAKBİM)
  • Sayfa Sayıları: ss.178-186
  • Anahtar Kelimeler: Walking exercises, middle-aged men, estimated maximal oxygen consumption, lipid profile, highly-sensitive C-reactive protein, soluble receptor activator of nuclear factor-kappa beta ligand
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Aim: To examine the effects of 10-week walking programs on maximal oxygen consumption, body composition, serum lipids, highly-sensitive C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand. Method: Twenty-seven middle-aged men (40-60years) walked for ten weeks, five days per week, 40-52min per day at either moderate or high intensity (∼5.95±0.26km/h and ∼7.64±0.36km/h; 50-55% and 70-75% maximum heart rate reserve, respectively). Non-walking, sedentary men served as controls (n=13). Estimated maximal oxygen consumption, body composition, lipid profile, highly-sensitive C-reactive protein, osteoprotegerin and soluble receptor activator of nuclear factor-kappaβ ligand were determined before and after the study. Results: After 10 weeks, estimated maximal oxygen consumption improved in both exercise groups (p<.05), favoring high-intensity group (p<.05). Body weight, percent body fat, and body mass index reduced significantly in both exercise groups (p<.05). Walking programs did not cause any significant changes in blood lipids, highly-sensitive Creactive protein, and osteoprotegerin levels; however, soluble receptor activator of nuclear factor-kappaβ ligand levels were found to decrease in high-intensity group (p<.05) and the change observed in both exercise groups was different from the change in control group (p<.05). Conclusion: For protective effects against cardiac risk factors and arterial calcification, high-intensity walking programs are advisable due to the greater improvements in soluble receptor activator of nuclear factor-kappaβ ligand and estimated maximal oxygen consumption. © TurkJBiochem.com.