The resistance of Pseudomonas aeruginosa strains to fluoroquinolone group of antibiotics


Algun U., Arisoy A., GÜNDÜZ T., Ozbakkaloglu B.

Indian Journal of Medical Microbiology, cilt.22, sa.2, ss.112-114, 2004 (Scopus) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 22 Sayı: 2
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1016/s0255-0857(21)02891-7
  • Dergi Adı: Indian Journal of Medical Microbiology
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.112-114
  • Anahtar Kelimeler: Fluoroquinolones, Pseudomonas aeruginosa, Resistance
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Fluoroquinolones are antibiotics that are very effective against many gram negative microorganisms, including P. aeruginosa. However, resistance to these antibiotics has been reported in recent years as well. In this study, the sensivity of 136 P. aeruginosa strains, isolated from various clinical materials, to fluoroquinolones has been investigated. The lowest resistance rate was in ciprofloxacin with 12.5%. The resistance rates of the others were as follows: norfloxacin 14.7%, levofloxacin 16.9%, ofloxacin 19.9% and pefloxacin 28.7%. The 88.2% of the resistant strains to all fluoroquinolones were originated from intensive care unit.