Akademik Veri Yönetim Sistemi
South African Journal of Botany, cilt.183, ss.229-242, 2025 (SCI-Expanded)
The interest of consumers in baobab products has been growing due to the exceptional phytochemical profile, bioactivity, and health effects of baobab. The aim of this study was to determine the optimum conditions for ultrasound-assisted extraction (UAE) to obtain bioactive-rich baobab fruit extracts using water in the context of green and sustainable chemistry. The ultrasound amplitude (40–100 %), organic baobab fruit pulp (OBFP) concentration (5–15 %, w/v), and ultrasonication time (5–15 min) were selected as independent variables. The predicted optimal conditions were 92.72 % ultrasound amplitude, 11.49 % OBFP, and 15 min of ultrasonication. Under these extraction conditions, total phenolics content (TPC), total flavonoids content (TFC), ascorbic acid content (AAC), DPPH-radical scavenging activity, and CIE a* and b* values were 2432.85 mg GAE/100 g, 7412.49 mg CE/100 g, 229.17 mg/100 g, 35.47 %, 4.85, and 14.78, respectively. The growth of Escherichia coli and Staphylococcus aureus was inhibited by the optimized extract at 6.25 mg/mL as the minimum inhibition concentration (MIC). The extract reduced the cell viability in MDA-MB-231 human breast cancer cells in a dose- and time-dependent manner, while it did not have toxicity against HEK293 human embryonic kidney cells. The obtained extract can be used as a natural thickener in various foods where high viscosity is desired.