Alopecia Universalis after Treatment with Simvastatin and Ezetimibe: Affects on Family Alopecia Universal após Tratamento com Sinvastatina e Ezetimiba: Impactos na Família

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Ozyurtlu F., ÇETİN N.

Arquivos Brasileiros de Cardiologia, cilt.119, sa.4, ss.631-633, 2022 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 119 Sayı: 4
  • Basım Tarihi: 2022
  • Doi Numarası: 10.36660/abc.20220187
  • Dergi Adı: Arquivos Brasileiros de Cardiologia
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus, EMBASE, MEDLINE, Directory of Open Access Journals
  • Sayfa Sayıları: ss.631-633
  • Anahtar Kelimeler: Alopecia, Atorvastatin/adverse effects, Autoimmune Diseases, Ezetimibe, Simvastatin Drug Combination/adverse effects, Genetic, Hypercholesterolemia
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Alopecia areata (AA) is an autoimmune disease that grows in the scalp or in other parts of the body. Alopecia universalis, which is a rare form of alopecia areata, is characterized by a loss of hair that affects the entire body. In the two patients presented in this study, atorvastatin t r eat ment was i mpl ement ed, wi t h t he di agnosi s of hypercholesterolemia; however, when the target values were not reached, a combination of simvastatin and ezetimibe was implemented. After a period of simvastatin/ ezetimibe treatment, the AA disorder, which began with hair loss on the scalp, spread to the entire body and turned into Alopecia Universalis. Although statins can cause alopecia with autoimmune reactions, they are generally used in the treatment of alopecia due to their immunomodulatory effects.