Stage is a prognostic factor for surgically treated patients with early-stage lip cancer for whom a 'wait and see' policy in terms of neck status has been implemented


ESKİİZMİR G., Ozgur E., Karaca G., TEMİZ P., Yanar N. H., Ozyurt B. C.

Journal of Laryngology and Otology, cilt.131, sa.10, ss.889-894, 2017 (SCI-Expanded) identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 131 Sayı: 10
  • Basım Tarihi: 2017
  • Doi Numarası: 10.1017/s0022215117001669
  • Dergi Adı: Journal of Laryngology and Otology
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.889-894
  • Anahtar Kelimeler: Carcinoma, Squamous Cell, Disease-Free Survival, Head And Neck Neoplasms, Lip Neoplasms, Local Neoplasm Recurrence, Prognosis, Survival
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Objectives: To determine the locoregional control and survival rates (in terms of risk factors) of patients who underwent surgical resection of early-stage lip cancer and for whom a 'wait and see' policy in terms of neck status had been implemented. Methods: The sociodemographic data, tumour stage, tumour characteristics and histopathological features of 41 patients with early-stage lip cancer were evaluated. Factors predictive of survival and locoregional recurrence were analysed. The five-year overall survival and disease-free survival rates were determined, and the prognostic risk factors were compared. Results: The mean follow-up period was 60.5 months (range, 4-92 months). Age, sex, tumour stage, tumour thickness and volume, and perineural involvement were not predictive of locoregional recurrence or survival. Pathological tumour stage (T1 vs T2) was a prognostic factor for both five-year overall survival (87.3 vs 65.6 per cent, p = 0.042) and disease-free survival (88.6 vs 65.6 per cent, p = 0.037). Conclusion: Tumour stage was clearly a major factor affecting the prognosis of surgically treated patients with early-stage lip cancer for whom a 'wait and see' policy in terms of neck status had been implemented.