Synthesis of Cycloalk[b]indole Bearing Spiropiperidine Derivatives


GÜNDOĞDU HIZLIATEŞ C., GÜLLE S., ERGÜN M. Y.

Journal of Heterocyclic Chemistry, cilt.53, sa.1, ss.249-254, 2016 (SCI-Expanded) identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 53 Sayı: 1
  • Basım Tarihi: 2016
  • Doi Numarası: 10.1002/jhet.2395
  • Dergi Adı: Journal of Heterocyclic Chemistry
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.249-254
  • Anahtar Kelimeler: indole containing compounds, piperidinedione, sedative and hypnotic drugs, Tetrahydrocarbazolones
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

(Chemical Equation Presented) The novel heterocyclic compounds that have cycloalk[b]indole moiety bearing spiropiperidinone and spiropiperidinedione (3a, 3b, 3c, 5a, 5b, 8a, 8b, and 10a) were synthesized for the first time. The synthesis of spiropiperidinone and spiropiperidinedione structures was performed by a new method. These compounds are similar to sedative and hypnotic drugs such as methyprylon, glutethimide, and thalidomide.