Serum brain-derived neurotrophic factor levels in conversion disorder: Comparative study with depression

DEVECİ A., AYDEMİR Ö., Taskin O., TANELİ F., ESEN DANACI A.

Psychiatry and Clinical Neurosciences, cilt.61, sa.5, ss.571-573, 2007 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 61 Sayı: 5
  • Basım Tarihi: 2007
  • Doi Numarası: 10.1111/j.1440-1819.2007.01710.x
  • Dergi Adı: Psychiatry and Clinical Neurosciences
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.571-573
  • Anahtar Kelimeler: BDNF, biological marker, conversion disorder, depression, stress
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

The aim of the present study was to compare serum brain-derived neurotrophic factor (BDNF) levels of patients with major depressive disorder (MDD) and conversion disorder (CD). Serum BDNF levels were measured in the following three groups: 15 CD patients without any comorbid diagnosis of psychiatric disorder, 24 patients with MDD, and 26 healthy subjects without any psychiatric diagnosis or psychiatric treatment. The serum BDNF level of the healthy control group (31.4 ± 8.8 ng/mL) was statistically higher than the level of the MDD group (21.2 ± 11.3 ng/mL) and the CD group (24.3 ± 9.0 ng/mL; P = 0.008). This suggests that BDNF level may play a similar role in the pathophysiology of MDD and CD. © 2007 The Authors.