E-test:: An alternative method for susceptibility testing of <i>Mycobacterium tuberculosis</i>

Akcali S., Cicek C., Surucuoglu S., Ozbakkaloglu B.

MEDICAL PRINCIPLES AND PRACTICE, no.4, pp.264-267, 2005 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Publication Date: 2005
  • Doi Number: 10.1159/000085747
  • Journal Name: MEDICAL PRINCIPLES AND PRACTICE
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.264-267
  • Manisa Celal Bayar University Affiliated: No

Abstract

Objective: The purpose of this study was to compare the agar proportion method with the E- test method for susceptibility testing of Mycobacterium tuberculosis. Materials and Methods: A total of 100 isolates were tested for isoniazid, rifampin, streptomycin and ethambutol susceptibility using an indirect- proportion method as well as the E- test method. Results: Categorical agreement between the methods was 100% for isoniazid, rifampin, streptomycin, and ethambutol. Conclusion: The E- test method appears to be an alternative method to agar proportion for testing the susceptibility of M. tuberculosis isolates to the first- line antituberculous agents. Copyright (C) 2005 S. Karger AG, Basel.