Air stable N-heterocyclic carbene silver complexes: synthesis, characterization, and antibacterial activity

DEMİR ATLI D., Aksu D.

Journal of Coordination Chemistry, vol.76, no.11-12, pp.1497-1506, 2023 (SCI-Expanded, Scopus) identifier identifier

  • Publication Type: Article / Article
  • Volume: 76 Issue: 11-12
  • Publication Date: 2023
  • Doi Number: 10.1080/00958972.2023.2251077
  • Journal Name: Journal of Coordination Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, Chemical Abstracts Core, Chimica, Metadex
  • Page Numbers: pp.1497-1506
  • Keywords: Benzimidazolium salt, N-heterocyclic carbene, silver complex, antibacterial studies
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

A new benzimidazolium salt containing a 2,5-dimethylbenzyl substituent and six N-heterocyclic carbene (NHC) silver complexes were prepared. The complexes were characterized by NMR, FTIR, and LC-MS spectroscopic methods and elemental analyses. They are stable in solution for a week. The antibacterial properties of the Ag(I) complexes against two Gram-positive and two Gram-negative bacteria were investigated. Inhibition zone and minimum inhibitory concentration (MIC) data establish that these NHC-Ag(I) complexes possess antibacterial activities; 2b showed the highest antibacterial activity overall against Gram-positive and Gram-negative bacteria.