Albendazole as an alternative therapeutic agent for childhood giardiasis in Turkey


YERELİ K., BALCIOĞLU İ. C., ERTAN P., Limoncu E., ONAĞ A. O.

Clinical Microbiology and Infection, cilt.10, sa.6, ss.527-529, 2004 (SCI-Expanded) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 10 Sayı: 6
  • Basım Tarihi: 2004
  • Doi Numarası: 10.1111/j.1198-743x.2004.00829.x
  • Dergi Adı: Clinical Microbiology and Infection
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.527-529
  • Anahtar Kelimeler: albendazole, Giardia lamblia, giardiasis, therapy
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

The efficacy of albendazole for the treatment of giardiasis has been indicated by previous in-vitro and in-vivo studies. In order to compare the therapeutic efficacy of albendazole and metronidazole, 107 Giardia-positive children (aged 3-15 years), diagnosed by three consecutive positive stool examinations, were enrolled in the study. Of these children, 52 were given a single daily dose of albendazole 10 mg/kg for 5 days, and 55 were given metronidazole 20 mg/kg daily in three doses for 7 days. Parasite eradication was achieved in 47 (90.4%) of 52 children treated with albendazole and 49 (89.1%) of 55 children treated with metronidazole (p > 0.05). These results suggest that albendazole is an effective treatment option for childhood giardiasis. © 2004 Copyright by the European Society of Clinical Microbiology and Infectious Diseases.