Generalized mean-field theory relating helix tilt in a bilayer to lipid disorder

Kayacan O.

Biophysical Chemistry, vol.111, no.3, pp.191-195, 2004 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 111 Issue: 3
  • Publication Date: 2004
  • Doi Number: 10.1016/j.bpc.2004.05.010
  • Journal Name: Biophysical Chemistry
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.191-195
  • Keywords: tsallis thermostatistics, membrane protein, helix tilt, lipid disorder, mean-field theory
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

We present a generalized theory relating the helix tilt angle in a bilayer to lipid disorder. In doing so, we consider a theory performed earlier [Biophys. Chem., 86 (2000) 79] and generalize it within a nonextensive formalism. The generalized theory provides a method to compare the rotational barriers for different helices in lipid bilayers, accounting for long-range interactions via a parameter which is called "entropic index". The results obtained could lead to point out future experiments which might shed light on lipid-protein interactions. © 2004 Published by Elsevier B.V.