Primary vaginal squamous cell carcinoma - the coeffect of vaginal leiomyoma and Human papillomavirus (HPV); A case report

MAVİLİ H. S., KANDİLOĞLU A. R., ATMIŞ Ö., UYAR Y.

Journal of Cancer Research and Therapeutics, vol.20, no.5, pp.1622-1624, 2024 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 20 Issue: 5
  • Publication Date: 2024
  • Doi Number: 10.4103/jcrt.jcrt_2108_22
  • Journal Name: Journal of Cancer Research and Therapeutics
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, Academic Search Premier, CAB Abstracts, CINAHL, MEDLINE, Veterinary Science Database
  • Page Numbers: pp.1622-1624
  • Keywords: HPV, vaginal leiomyoma, vaginal squamous cell carcinoma
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

Primary vaginal squamous cell carcinoma (SCC) is extremely rare. Primer vaginal SSC developed by the coeffect of leiomyoma and Human papillomavirus (HPV) is presented. We report a case of primary vaginal SCC in a 62-year-old woman presenting dyspareunia. On macroscopic examination, the surface of the operation material was partly ulcerated. On the cut surface, the material was solid, firm, white, and whorled. Microscopic examination revealed leiomyoma ulcerating the mucosa and SCC at the base of the ulcer. The case, in which vaginal SCC developed in the vagina due to the irritation of the leiomyoma, as well as its relationship with HPV, is important to be the first to our knowledge.