Relationship between IL-6 and COVID-19: To be considered during treatment

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VATANSEVER H. S., Becer E.

Future Virology, vol.15, no.12, pp.817-822, 2020 (SCI-Expanded, Scopus) identifier

  • Publication Type: Article / Review
  • Volume: 15 Issue: 12
  • Publication Date: 2020
  • Doi Number: 10.2217/fvl-2020-0168
  • Journal Name: Future Virology
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus, BIOSIS, Chemical Abstracts Core, EMBASE
  • Page Numbers: pp.817-822
  • Keywords: COVID-19, cytokine, cytokine storm, IL-6, SARS-CoV-2
  • Open Archive Collection: AVESIS Open Access Collection
  • Manisa Celal Bayar University Affiliated: Yes

Abstract

The detection and control of pro-inflammatory response is crucial in the early stages of viral infection. Coronavirus disease 2019 (COVID-19) is an emerging viral disease of global concern and optimal treatment has yet to be determined. Unknown response of treatment of COVID-19 is important during patient monitoring. IL-6 is one of the key cytokines after activated macrophages. Therefore, control of systemic IL-6 levels in SARS-CoV-2 infected patients may be a parameter for COVID-19 disease. This review is focused on the induction of IL-6 after viral infections as a target molecule for monitoring cellular response.