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Turkiye Klinikleri Dermatoloji, vol.34, no.3, pp.117-120, 2024 (Scopus)
Cutaneous angiofibroma is a group of lesions that show similar histological features, but different clinical findings and can be divided into four subgroups: fibrous papule, adenoma sebaceum, periungual fibroma (Koenen tumors) and pearly penile papules of the penis. Facial angiofibromas are one of the diagnostic clinical findings of tuberous sclerosis. Although less common, it has also been reported in cases with multiple endocrine neoplasia Type 1, Birt-Hogg-Dubé syndrome, neurofibromatosis Type 2 and Cowden syndrome. It may also occur isolated without accompanying any systemic syndrome, as in our case. There is a report of four cases with bilateral multiple facial cutaneous angiofibromas that are not accompanied by any syndrome, and no other publication has been found in the literature. In this report, a twelve-year-old male patient with bilateral facial cutaneous angiofibromas, unaccompanied by systemic findings, is presented with its clinical, genetic, dermoscopical and histopathological findings.