Efficacy of 5% imiquimod cream in a patient with classic kaposi sarcoma


Creative Commons License

GÜNDÜZ K., Günay Ü., İNANIR I., Gençoǧlan G., TEMİZ P.

Journal of Dermatological Case Reports, cilt.6, sa.2, ss.52-53, 2012 (Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 6 Sayı: 2
  • Basım Tarihi: 2012
  • Doi Numarası: 10.3315/jdcr.2012.1099
  • Dergi Adı: Journal of Dermatological Case Reports
  • Derginin Tarandığı İndeksler: Scopus
  • Sayfa Sayıları: ss.52-53
  • Anahtar Kelimeler: imiquimod, Kaposi sarcoma, skin cancer, treatment
  • Manisa Celal Bayar Üniversitesi Adresli: Evet

Özet

Background: The classic Kaposi sarcoma is most common in the Mediterranean po-pulation over 50 years of age and presents with reddish-brown papules and nodules particularly on the lower limbs. Treatment depends on the clinical presentation and extension of lesions. Imiquimod is as an immune response modifier with antiangio-genic activity. Main observations: We present a 74-year-old man with classic Kaposi sarcoma who had multiple, small, violaceous papules and nodules on the trunk and extremities with a history of 14 years. He complained particularly from plantar hyperkeratotic painful nodules. Treatment with imiquimod 5% cream under occlusion resulted with almost complete regression within 12 weeks. No local or systemic side effects were observed. Conclusions: Topical imiquimod was a safe and effective therapy in our patient with classic Kaposi sarcoma.