Synthesis of perfluoroalkylated β-alanine and some peptide derivatives:: an access to original surfactants

Özer M. S., Gérardin-Charbonnier C., Thiébaut S., Rodehüser L., Selve C.

AMINO ACIDS, cilt.16, sa.3-4, ss.381-389, 1999 (SCI-Expanded, Scopus) identifier identifier identifier

  • Yayın Türü: Makale / Tam Makale
  • Cilt numarası: 16 Sayı: 3-4
  • Basım Tarihi: 1999
  • Doi Numarası: 10.1007/bf01388177
  • Dergi Adı: AMINO ACIDS
  • Derginin Tarandığı İndeksler: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Sayfa Sayıları: ss.381-389
  • Manisa Celal Bayar Üniversitesi Adresli: Hayır

Özet

The reaction of amines or sodium azide with 3-perfluoroalkyl-3-fluoroprop-2-enoate, followed by hydrogenation, affords perfluoroalkylated beta-alanine analogues in very good yields. These compounds can be linked via an amide bond to produce peptide analogues such as carnosine or carcinine derivatives, which could have surfactive and complexing properties.