Synthesis of perfluoroalkylated β-alanine and some peptide derivatives:: an access to original surfactants

Özer M. S., Gérardin-Charbonnier C., Thiébaut S., Rodehüser L., Selve C.

AMINO ACIDS, vol.16, no.3-4, pp.381-389, 1999 (SCI-Expanded, Scopus) identifier identifier identifier

  • Publication Type: Article / Article
  • Volume: 16 Issue: 3-4
  • Publication Date: 1999
  • Doi Number: 10.1007/bf01388177
  • Journal Name: AMINO ACIDS
  • Journal Indexes: Science Citation Index Expanded (SCI-EXPANDED), Scopus
  • Page Numbers: pp.381-389
  • Manisa Celal Bayar University Affiliated: No

Abstract

The reaction of amines or sodium azide with 3-perfluoroalkyl-3-fluoroprop-2-enoate, followed by hydrogenation, affords perfluoroalkylated beta-alanine analogues in very good yields. These compounds can be linked via an amide bond to produce peptide analogues such as carnosine or carcinine derivatives, which could have surfactive and complexing properties.